Technology

Leader in the Field of Controlled Release Preparations

GoeGoe Honglin Pharmaceutical Co. (GoeGoe Honglin Pharm.) has mastered several modified-release technologies such as sustained-release pellets, enteric-coated pellets, and osmotically controlled release tablets, and applied them to our marketed products, JUPOPHON®, Kelanmei®, JUPOPINE® and RoToFier®. We’re ready to apply these technologies to other drugs in collaboration with our partners. Our technology capacity reflects our long-standing commitment to contributing to the society.

GoeGoe Honglin Pharm. further expanded the technology from ALZA Corporation — the originator of osmotic pump controlled release technology.

OROS (Osmotic Controlled- Release Oral Delivery System)

This technology, known as OROS (Osmotic Controlled-Release Oral Delivery System), involved the osmotic design of the tablet's core, which contained both the drug and osmotic agent and a semi-permeable membrane. It’s an advanced drug delivery technology that controls the release rate of medications in tablet form through the osmotic pressure inside the membrane. When a patient swallows an OROS tablet, water is drawn through the membrane to saturate the drug, which is then released in liquid form drop by drop through laser-drilled holes in the tablet. This permits a gradual release of the drug and leads to reduced side effects and predictable levels of the drug in the bloodstream.

  • A specialized overseas R&D team

    Driven by the passion to contribute to the pharmaceutical industry, GoeGoe Honglin Pharm. has established a specialized overseas R&D team. Dr. Huang, one of the core members, holds a doctoral degree from the University of Michigan (U.S.A.) and has served successively in internationally renowned pharmaceutical giants such as Merck Sharp & Dohme Co., Inc. ALZA Corporation and Johnson&Johnson, boasting profound technical accumulation and extensive industry experience. Furthermore, we have specially invited the patent inventor of the controlled-release technology to provide technical support, realizing the precise implementation and systematic inheritance of this core technology.

  • World's first controlled-release tablet drilling machine

    Notably, in recognition of GoeGoe Honglin Pharm.'s remarkable contributions to the inheritance of controlled-release technology and as an affirmation of our technical strength, ALZA Corporation has presented to our company a true antique — the world's first fully automatic mechanical drilling machine used for controlled-release tablet testing — for commemoration. This gesture holds profound significance, further demonstrating GoeGoe Honglin Pharm.'s outstanding technical capabilities in the field.

  • Controlled-release technology platform with independent patents

    After multiple generations of technological upgrades, we have established a controlled-release technology platform with independent formulation patents, developing controlled-release products that achieve zero-order rate release. These products feature stable blood drug concentrations, therapeutic effects, fewer side effects, as the products based on the innovator’s technology and greater suitability for long-term use, making them a trusted choice among physicians and patients.